Chicken intestine: an alternative to the mammalian intestine for physiology experimentation
نویسندگان
چکیده
منابع مشابه
How to make an intestine.
With the high prevalence of gastrointestinal disorders, there is great interest in establishing in vitro models of human intestinal disease and in developing drug-screening platforms that more accurately represent the complex physiology of the intestine. We will review how recent advances in developmental and stem cell biology have made it possible to generate complex, three-dimensional, human ...
متن کاملIdentification of the Paneth cells in chicken small intestine.
The Paneth cells are highly specialized cells in the epithelium of the small intestine of many vertebrate species. These cells reside at the base of crypts of the Lieberkühn and contain abundant secretory granules. Previous studies suggesting the existence of Paneth cells in the chicken (Gallus gallus) remained controversial. Here we seek to identify the Paneth cells in the chicken small intest...
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The distribution of non-specific alkaline phosphatase (AP) in normal duodenum, rest small intestine and caecum of chicken has been studied by a catalytic histochemistry method. Embryos and chickens ranging between day 11 prior to and day 60 after hatching were used and the findings of AP reaction were correlated with the age. In the small intestine, during foetal life, the AP activity started t...
متن کاملCholinergic regulation of epithelial ion transport in the mammalian intestine.
Acetylcholine (ACh) is critical in controlling epithelial ion transport and hence water movements for gut hydration. Here we review the mechanism of cholinergic control of epithelial ion transport across the mammalian intestine. The cholinergic nervous system affects basal ion flux and can evoke increased active ion transport events. Most studies rely on measuring increases in short-circuit cur...
متن کاملDefensins and Innate Immunity of the Mammalian Small Intestine
The release of gene-encoded antimicrobial peptides by epithelial cells is thought to contribute to innate mucosal immunity. Defensins are a predominant class of such antimicrobial peptides in mammals. These cysteine-rich cationic peptides have antibiotic activity against a wide range of bacteria and other microbes. In the mammalian small intestine, Paneth cells at the base of the crypts of Lieb...
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ژورنال
عنوان ژورنال: Advances in Physiology Education
سال: 2018
ISSN: 1043-4046,1522-1229
DOI: 10.1152/advan.00031.2018